Protection of Antigen-Primed Effector T Cells From Glucocorticoid-Induced Apoptosis in Cell Culture and in a Mouse Model of Multiple Sclerosis

Induction of T cell apoptosis constitutes a major mechanism by which therapeutically administered glucocorticoids (GCs) suppress inflammation and associated clinical symptoms, for instance in multiple sclerosis (MS) patients suffering from an acute relapse. The sensitivity of T cells to GC action de...

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Vydáno v:Front Immunol
Hlavní autoři: Bier, Jasmina, Steiger, Sebastian M., Reichardt, Holger M., Lühder, Fred
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2021
Témata:
Immunology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8222504/
https://ncbi.nlm.nih.gov/pubmed/34177911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.671258
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