Multiparametric characterization of white matter alterations in early stage Huntington disease

Huntington’s disease (HD) is a monogenic, fully penetrant neurodegenerative disorder. Widespread white matter damage affects the brain of patients with HD at very early stages of the disease. Fixel-based analysis (FBA) is a novel method to investigate the contribution of individual crossing fibers t...

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Udgivet i:Sci Rep
Main Authors: Adanyeguh, Isaac M., Branzoli, Francesca, Delorme, Cécile, Méneret, Aurélie, Monin, Marie-Lorraine, Luton, Marie-Pierre, Durr, Alexandra, Sabidussi, Emanoel, Mochel, Fanny
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8222368/
https://ncbi.nlm.nih.gov/pubmed/34162958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-92532-1
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