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Energy deficit in Huntington disease: why it matters

Huntington disease (HD) is an autosomal dominant neurodegenerative disease with complete penetrance. Although the understanding of the cellular mechanisms that drive neurodegeneration in HD and account for the characteristic pattern of neuronal vulnerability is incomplete, defects in energy metaboli...

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Autors principals: Mochel, Fanny, Haller, Ronald G.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3026743/
https://ncbi.nlm.nih.gov/pubmed/21285522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI45691
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