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AAV-mediated in vivo CAR gene therapy for targeting human T-cell leukemia

Chimeric antigen receptor (CAR) T-cell therapy is the most active field in immuno-oncology and brings substantial benefit to patients with B cell malignancies. However, the complex procedure for CAR T-cell generation hampers its widespread applications. Here, we describe a novel approach in which hu...

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Vydáno v:Blood Cancer J
Hlavní autoři: Nawaz, Waqas, Huang, Bilian, Xu, Shijie, Li, Yanlei, Zhu, Linjing, Yiqiao, Hu, Wu, Zhiwei, Wu, Xilin
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8222347/
https://ncbi.nlm.nih.gov/pubmed/34162832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41408-021-00508-1
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