A single-domain antibody inhibits SFTSV and mitigates virus-induced pathogenesis in vivo

Severe fever with thrombocytopenia syndrome virus (SFTSV) is a novel tick-borne bunyavirus that recently emerged in East Asian countries. SFTS is characterized by high fever, thrombocytopenia, leukopenia, multiorgan failure, and hemorrhage with case fatality rates of 6.3% to 30%. Neither antivirals...

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Dades bibliogràfiques
Publicat a:JCI Insight
Autors principals: Wu, Xilin, Li, Yanlei, Huang, Bilian, Ma, Xiaohua, Zhu, Linjing, Zheng, Nan, Xu, Shijie, Nawaz, Waqas, Xu, Changping, Wu, Zhiwei
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2020
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7406269/
https://ncbi.nlm.nih.gov/pubmed/32641581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.136855
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