Irreversible electroporation augments checkpoint immunotherapy in prostate cancer and promotes tumor antigen-specific tissue-resident memory CD8+ T cells

Memory CD8+ T cells populate non-lymphoid tissues (NLTs) following pathogen infection, but little is known about the establishment of endogenous tumor-specific tissue-resident memory T cells (T(RM)) during cancer immunotherapy. Using a transplantable mouse model of prostate carcinoma, here we report...

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Enregistré dans:
Détails bibliographiques
Publié dans:Nat Commun
Auteurs principaux: Burbach, Brandon J., O’Flanagan, Stephen D., Shao, Qi, Young, Katharine M., Slaughter, Joseph R., Rollins, Meagan R., Street, Tami Jo L., Granger, Victoria E., Beura, Lalit. K., Azarin, Samira M., Ramadhyani, Satish, Forsyth, Bruce R., Bischof, John C., Shimizu, Yoji
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2021
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8222297/
https://ncbi.nlm.nih.gov/pubmed/34162858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-24132-6
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