Irreversible electroporation augments checkpoint immunotherapy in prostate cancer and promotes tumor antigen-specific tissue-resident memory CD8+ T cells

Memory CD8+ T cells populate non-lymphoid tissues (NLTs) following pathogen infection, but little is known about the establishment of endogenous tumor-specific tissue-resident memory T cells (T(RM)) during cancer immunotherapy. Using a transplantable mouse model of prostate carcinoma, here we report...

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Publicado no:Nat Commun
Main Authors: Burbach, Brandon J., O’Flanagan, Stephen D., Shao, Qi, Young, Katharine M., Slaughter, Joseph R., Rollins, Meagan R., Street, Tami Jo L., Granger, Victoria E., Beura, Lalit. K., Azarin, Samira M., Ramadhyani, Satish, Forsyth, Bruce R., Bischof, John C., Shimizu, Yoji
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8222297/
https://ncbi.nlm.nih.gov/pubmed/34162858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-24132-6
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