Nalaganje...
CGRP, adrenomedullin and adrenomedullin 2 display endogenous GPCR agonist bias in primary human cardiovascular cells
Agonist bias occurs when different ligands produce distinct signalling outputs when acting at the same receptor. However, its physiological relevance is not always clear. Using primary human cells and gene editing techniques, we demonstrate endogenous agonist bias with physiological consequences for...
Shranjeno v:
| izdano v: | Commun Biol |
|---|---|
| Main Authors: | , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Publishing Group UK
2021
|
| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8222276/ https://ncbi.nlm.nih.gov/pubmed/34163006 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-021-02293-w |
| Oznake: |
Označite
Brez oznak, prvi označite!
|