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Immunodominant T-cell epitopes from the SARS-CoV-2 spike antigen reveal robust pre-existing T-cell immunity in unexposed individuals

The COVID-19 pandemic has revealed a range of disease phenotypes in infected patients with asymptomatic, mild, or severe clinical outcomes, but the mechanisms that determine such variable outcomes remain unresolved. In this study, we identified immunodominant CD8 T-cell epitopes in the spike antigen...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Mahajan, Swapnil, Kode, Vasumathi, Bhojak, Keshav, Karunakaran, Coral, Lee, Kayla, Manoharan, Malini, Ramesh, Athulya, HV, Sudheendra, Srivastava, Ankita, Sathian, Rekha, Khan, Tahira, Kumar, Prasanna, Gupta, Ravi, Chakraborty, Papia, Chaudhuri, Amitabha
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8222233/
https://ncbi.nlm.nih.gov/pubmed/34162945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-92521-4
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