Structural basis of GABA(B) receptor–G(i) protein coupling

G-protein-coupled receptors (GPCRs) have central roles in intercellular communication(1,2). Structural studies have revealed how GPCRs can activate G proteins. However, whether this mechanism is conserved among all classes of GPCR remains unknown. Here we report the structure of the class-C heterodi...

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Vydáno v:Nature
Hlavní autoři: Shen, Cangsong, Mao, Chunyou, Xu, Chanjuan, Jin, Nan, Zhang, Huibing, Shen, Dan-Dan, Shen, Qingya, Wang, Xiaomei, Hou, Tingjun, Chen, Zhong, Rondard, Philippe, Pin, Jean-Philippe, Zhang, Yan, Liu, Jianfeng
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2021
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8222003/
https://ncbi.nlm.nih.gov/pubmed/33911284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-021-03507-1
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