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Cryo-EM structures of inactive and active GABA(B) receptor

Metabotropic GABA(B) G protein-coupled receptor functions as a mandatory heterodimer of GB1 and GB2 subunits and mediates inhibitory neurotransmission in the central nervous system. Each subunit is composed of the extracellular Venus flytrap (VFT) domain and transmembrane (TM) domain. Here we presen...

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Detalhes bibliográficos
Publicado no:Cell Res
Main Authors: Mao, Chunyou, Shen, Cangsong, Li, Chuntao, Shen, Dan-Dan, Xu, Chanjuan, Zhang, Shenglan, Zhou, Rui, Shen, Qingya, Chen, Li-Nan, Jiang, Zhinong, Liu, Jianfeng, Zhang, Yan
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Singapore 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7343782/
https://ncbi.nlm.nih.gov/pubmed/32494023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41422-020-0350-5
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