Cryo-EM structures of inactive and active GABA(B) receptor

Metabotropic GABA(B) G protein-coupled receptor functions as a mandatory heterodimer of GB1 and GB2 subunits and mediates inhibitory neurotransmission in the central nervous system. Each subunit is composed of the extracellular Venus flytrap (VFT) domain and transmembrane (TM) domain. Here we presen...

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Bibliografiske detaljer
Udgivet i:Cell Res
Main Authors: Mao, Chunyou, Shen, Cangsong, Li, Chuntao, Shen, Dan-Dan, Xu, Chanjuan, Zhang, Shenglan, Zhou, Rui, Shen, Qingya, Chen, Li-Nan, Jiang, Zhinong, Liu, Jianfeng, Zhang, Yan
Format: Artigo
Sprog:Inglês
Udgivet: Springer Singapore 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7343782/
https://ncbi.nlm.nih.gov/pubmed/32494023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41422-020-0350-5
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