Ultrapotent miniproteins targeting the SARS-CoV-2 receptor-binding domain protect against infection and disease

Despite the introduction of public health measures and spike protein-based vaccines to mitigate the COVID-19 pandemic, SARS-CoV-2 infections and deaths continue to have a global impact. Previously, we used a structural design approach to develop picomolar range miniproteins targeting the SARS-CoV-2...

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Vydáno v:Cell Host Microbe
Hlavní autoři: Case, James Brett, Chen, Rita E., Cao, Longxing, Ying, Baoling, Winkler, Emma S., Johnson, Max, Goreshnik, Inna, Pham, Minh N., Shrihari, Swathi, Kafai, Natasha M., Bailey, Adam L., Xie, Xuping, Shi, Pei-Yong, Ravichandran, Rashmi, Carter, Lauren, Stewart, Lance, Baker, David, Diamond, Michael S.
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier Inc. 2021
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8221914/
https://ncbi.nlm.nih.gov/pubmed/34192518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2021.06.008
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