Notch1 switches progenitor competence in inducing medulloblastoma

The identity of the cell of origin is a key determinant of cancer subtype, progression, and prognosis. Group 3 medulloblastoma (MB) is a malignant childhood brain cancer with poor prognosis and few candidates as putative cell of origin. We overexpressed the group 3 MB genetic drivers MYC and Gfi1 in...

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Dades bibliogràfiques
Publicat a:Sci Adv
Autors principals: Ballabio, Claudio, Gianesello, Matteo, Lago, Chiara, Okonechnikov, Konstantin, Anderle, Marica, Aiello, Giuseppe, Antonica, Francesco, Zhang, Tingting, Gianno, Francesca, Giangaspero, Felice, Hassan, Bassem A., Pfister, Stefan M., Tiberi, Luca
Format: Artigo
Idioma:Inglês
Publicat: American Association for the Advancement of Science 2021
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8221631/
https://ncbi.nlm.nih.gov/pubmed/34162555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abd2781
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