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Notch1 switches progenitor competence in inducing medulloblastoma
The identity of the cell of origin is a key determinant of cancer subtype, progression, and prognosis. Group 3 medulloblastoma (MB) is a malignant childhood brain cancer with poor prognosis and few candidates as putative cell of origin. We overexpressed the group 3 MB genetic drivers MYC and Gfi1 in...
Tallennettuna:
| Julkaisussa: | Sci Adv |
|---|---|
| Päätekijät: | , , , , , , , , , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
American Association for the Advancement of Science
2021
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8221631/ https://ncbi.nlm.nih.gov/pubmed/34162555 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abd2781 |
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