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Effect of exposure to 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) and polychlorinated biphenyls (PCBs) on mitochondrial DNA (mtDNA) copy number in rats

Mitochondria are intracellular organelles responsible for biological oxidation and energy production. These organelles are susceptible to damage from oxidative stress and compensate for damage by increasing the number of copies of their own genome, mitochondrial DNA (mtDNA). Cancer and environmental...

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Dettagli Bibliografici
Pubblicato in:Toxicology
Autori principali: VanEtten, Samantha L., Bonner, Matthew R., Ren, Xuefeng, Birnbaum, Linda S., Kostyniak, Paul J., Wang, Jie, Olson, James R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8220889/
https://ncbi.nlm.nih.gov/pubmed/33677009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tox.2021.152744
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