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Effect of exposure to 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) and polychlorinated biphenyls (PCBs) on mitochondrial DNA (mtDNA) copy number in rats

Mitochondria are intracellular organelles responsible for biological oxidation and energy production. These organelles are susceptible to damage from oxidative stress and compensate for damage by increasing the number of copies of their own genome, mitochondrial DNA (mtDNA). Cancer and environmental...

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Detalhes bibliográficos
Publicado no:Toxicology
Main Authors: VanEtten, Samantha L., Bonner, Matthew R., Ren, Xuefeng, Birnbaum, Linda S., Kostyniak, Paul J., Wang, Jie, Olson, James R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8220889/
https://ncbi.nlm.nih.gov/pubmed/33677009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tox.2021.152744
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