T-614 attenuates knee osteoarthritis via regulating Wnt/β-catenin signaling pathway

BACKGROUND: The aim of this study was to investigate the effect of Iguratimod (T-614) on rat knee osteoarthritis (KOA) and further to explore its underlying mechanism. METHODS: In this study, papain-induced KOA model was constructed. Hematoxylin and eosin (H&E) staining was conducted to observe...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Orthop Surg Res
Prif Awduron: Cong, Shan, Meng, Yan, Wang, Lingrui, Sun, Jiao, shi·Nu er xia ti, Ta bu, Luo, Li
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2021
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC8220752/
https://ncbi.nlm.nih.gov/pubmed/34158084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13018-021-02530-2
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