The redox-senescence axis and its therapeutic targeting

SIGNIFICANCE: Cellular growth arrest, associated with ‘senescence’, helps to safeguard against the accumulation of DNA damage which is often recognized as the underlying mechanism of a wide variety of age-related pathologies including cancer. Cellular senescence has also been described as a ‘double-...

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Detalhes bibliográficos
Publicado no:Redox Biol
Main Authors: Ngoi, Natalie YL., Liew, Angeline QX., Chong, Stephen J.F., Davids, Matthew S., Clement, Marie-Veronique, Pervaiz, Shazib
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2021
Assuntos:
Articles from Special Issue on Redox Roles in Cancer edited by Anita Hjelmeland
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8220395/
https://ncbi.nlm.nih.gov/pubmed/34147844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2021.102032
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