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Spaceflight decelerates the epigenetic clock orchestrated with a global alteration in DNA methylome and transcriptome in the mouse retina

Astronauts exhibit an assortment of clinical abnormalities in their eyes during long-duration spaceflight. The purpose of this study was to determine whether spaceflight induces epigenomic and transcriptomic reprogramming in the retina or alters the epigenetic clock. The mice were flown for 37 days...

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Detalhes bibliográficos
Publicado no:Precis Clin Med
Main Authors: Chen, Zhong, Stanbouly, Seta, Nishiyama, Nina C, Chen, Xin, Delp, Michael D, Qiu, Hongyu, Mao, Xiao W, Wang, Charles
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8220224/
https://ncbi.nlm.nih.gov/pubmed/34179686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/pcmedi/pbab012
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