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Spaceflight decelerates the epigenetic clock orchestrated with a global alteration in DNA methylome and transcriptome in the mouse retina

Astronauts exhibit an assortment of clinical abnormalities in their eyes during long-duration spaceflight. The purpose of this study was to determine whether spaceflight induces epigenomic and transcriptomic reprogramming in the retina or alters the epigenetic clock. The mice were flown for 37 days...

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Dettagli Bibliografici
Pubblicato in:Precis Clin Med
Autori principali: Chen, Zhong, Stanbouly, Seta, Nishiyama, Nina C, Chen, Xin, Delp, Michael D, Qiu, Hongyu, Mao, Xiao W, Wang, Charles
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8220224/
https://ncbi.nlm.nih.gov/pubmed/34179686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/pcmedi/pbab012
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