PDCD1 Polymorphisms May Predict Response to Anti-PD-1 Blockade in Patients With Metastatic Melanoma

A significant number of patients (pts) with metastatic melanoma do not respond to anti-programmed cell death 1 (PD1) therapies. Identifying predictive biomarkers therefore remains an urgent need. We retrospectively analyzed plasma DNA of pts with advanced melanoma treated with PD-1 antibodies, nivol...

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Détails bibliographiques
Publié dans:Front Immunol
Auteurs principaux: Parakh, Sagun, Musafer, Ashan, Paessler, Sabrina, Witkowski, Tom, Suen, Connie S. N. Li Wai, Tutuka, Candani S. A., Carlino, Matteo S., Menzies, Alexander M., Scolyer, Richard A., Cebon, Jonathan, Dobrovic, Alexander, Long, Georgina V., Klein, Oliver, Behren, Andreas
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2021
Sujets:
Immunology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8220213/
https://ncbi.nlm.nih.gov/pubmed/34177913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.672521
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