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Zinc supplementation augments the suppressive effects of repurposed NF-κB inhibitors on ACE2 expression in human lung cell lines

AIMS: Angiotensin-converting enzyme 2 (ACE2) is a key negative regulator of the renin-angiotensin system and also a major receptor for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Here, we reveal a role for NF-κB in human lung cell expression of ACE2, and we further explor...

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Detalhes bibliográficos
Publicado no:Life Sci
Main Authors: Lee, Ming-Cheng, Chen, Yin-Kai, Tsai-Wu, Jyy-Jih, Hsu, Yih-Jen, Lin, Bor-Ru
Formato: Artigo
Idioma:Inglês
Publicado em: The Authors. Published by Elsevier Inc. 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8219909/
https://ncbi.nlm.nih.gov/pubmed/34171382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.lfs.2021.119752
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