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The combined action of CTCF and its testis-specific paralog BORIS is essential for spermatogenesis
CTCF is a key organizer of the 3D genome. Its specialized paralog, BORIS, heterodimerizes with CTCF but is expressed only in male germ cells and in cancer states. Unexpectedly, BORIS-null mice have only minimal germ cell defects. To understand the CTCF-BORIS relationship, mouse models with varied CT...
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| Publicat a: | Nat Commun |
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| Autors principals: | , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group UK
2021
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8219828/ https://ncbi.nlm.nih.gov/pubmed/34158481 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-24140-6 |
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