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Dissecting regulatory pathways for transcription recovery following DNA damage reveals a non-canonical function of the histone chaperone HIRA

Transcription restart after a genotoxic challenge is a fundamental yet poorly understood process. Here, we dissect the interplay between transcription and chromatin restoration after DNA damage by focusing on the human histone chaperone complex HIRA, which is required for transcription recovery post...

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Bibliografiske detaljer
Udgivet i:Nat Commun
Main Authors: Bouvier, Déborah, Ferrand, Juliette, Chevallier, Odile, Paulsen, Michelle T., Ljungman, Mats, Polo, Sophie E.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8219801/
https://ncbi.nlm.nih.gov/pubmed/34158510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-24153-1
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