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MLS128 antibody-induced suppression of colon cancer cell growth is mediated by a desmocollin and a 110 kDa glycoprotein

Protein glycosylation is a diverse form of post-translational modification. Two to three consecutive O-linked N-acetylgalactosamines (Tn-antigens) are recognized by antibodies such as MLS128. MLS128 mAb inhibited cell growth and bound to a 110 kDa glycoprotein (GP) in LS180 and HT29 colon cancer cel...

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Detalhes bibliográficos
Publicado no:Biosci Trends
Main Authors: Shuck, Sarah C., Hong, Teresa, Kalkum, Markus, Igarashi, Ryo, Kajiya, Kota, Termini, John, Yamamoto, Kazuo, Fujita-Yamaguchi, Yoko
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8219476/
https://ncbi.nlm.nih.gov/pubmed/31168022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5582/bst.2019.01074
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