Expression of B7-H4 and IDO1 is associated with drug resistance and poor prognosis in high-grade serous ovarian carcinomas

High-grade serous ovarian carcinoma (HGSC) is the most lethal gynecologic malignancy. While immune checkpoint inhibitors against PD-L1 and CTLA-4 have shown significant effects in multiple tumor types, the response rate to single-agent immune checkpoint inhibitors is low in HGSC. Alternative biomark...

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Bibliographic Details
Published in:Hum Pathol
Main Authors: Niu, Na, Shen, Weiwei, Zhong, Yanping, Bast, Robert C., Jazaeri, Amir, Sood, Anil K., Liu, Jinsong
Format: Artigo
Language:Inglês
Published: 2021
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8219231/
https://ncbi.nlm.nih.gov/pubmed/33887301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.humpath.2021.04.003
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