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High expression of Tie-2 predicts poor prognosis in primary high grade serous ovarian cancer

BACKGROUND: Antiangiogenic therapy, although part of standard treatment in ovarian cancer, has variable efficacy. Furthermore, little is known about the prognostic biomarkers and factors influencing angiogenesis in cancer tissue. We evaluated the expression of angiopoietin-2 and two endothelial tyro...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Sopo, Minna, Sallinen, Hanna, Hämäläinen, Kirsi, Kivelä, Annukka, Ylä-Herttuala, Seppo, Kosma, Veli-Matti, Keski-Nisula, Leea, Anttila, Maarit
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7644024/
https://ncbi.nlm.nih.gov/pubmed/33151982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0241484
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