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High expression of Tie-2 predicts poor prognosis in primary high grade serous ovarian cancer

BACKGROUND: Antiangiogenic therapy, although part of standard treatment in ovarian cancer, has variable efficacy. Furthermore, little is known about the prognostic biomarkers and factors influencing angiogenesis in cancer tissue. We evaluated the expression of angiopoietin-2 and two endothelial tyro...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Sopo, Minna, Sallinen, Hanna, Hämäläinen, Kirsi, Kivelä, Annukka, Ylä-Herttuala, Seppo, Kosma, Veli-Matti, Keski-Nisula, Leea, Anttila, Maarit
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2020
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7644024/
https://ncbi.nlm.nih.gov/pubmed/33151982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0241484
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