Pharmacogene Sequencing of a Gabonese Population with Severe Plasmodium falciparum Malaria Reveals Multiple Novel Variants with Putative Relevance for Antimalarial Treatment

Malaria remains one of the deadliest diseases in Africa, particularly for children. While successful in reducing morbidity and mortality, antimalarial treatments are also a major cause of adverse drug reactions (ADRs). Host genetic variation in genes involved in drug disposition or toxicity constitu...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Pernaute-Lau, Leyre, Adegnika, Ayola Akim, Zhou, Yitian, Zinsou, Jeannot F., Gil, Jose Pedro, Krishna, Sanjeev, Kremsner, Peter G., Lauschke, Volker M., Velavan, Thirumalaisamy P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2021
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8218688/
https://ncbi.nlm.nih.gov/pubmed/33875422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00275-21
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados