Molecular markers of anti-malarial drug resistance in Central, West and East African children with severe malaria

BACKGROUND: The Plasmodium falciparum multidrug resistance 1 (PfMDR1), P. falciparum Ca(2+)-ATPase (PfATP6) and Kelch-13 propeller domain (PfK13) loci are molecular markers of parasite susceptibility to anti-malarial drugs. Their frequency distributions were determined in the isolates collected from...

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Publicat a:Malar J
Autors principals: Nguetse, Christian N., Adegnika, Ayola Akim, Agbenyega, Tsiri, Ogutu, Bernhards R., Krishna, Sanjeev, Kremsner, Peter G., Velavan, Thirumalaisamy P.
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2017
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5442681/
https://ncbi.nlm.nih.gov/pubmed/28535801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12936-017-1868-y
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