LRRK2-NFATc2 Pathway Associated with Neuroinflammation May Be a Potential Therapeutic Target for Parkinson’s Disease

Neuroinflammation plays an important role in the pathogenesis of Parkinson’s disease (PD). However, the molecular mechanisms involved in extracellular α‑synuclein-induced proinflammatory microglial responses through Toll-like receptor 2 (TLR2) are unclear. Leucine-rich repeat kinase 2 (LRRK2) is a s...

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Detaylı Bibliyografya
Yayımlandı:J Inflamm Res
Asıl Yazarlar: Wang, Youcui, Zhang, Xiaoqin, Chen, Fenghua, Chen, Leilei, Wang, Jun, Xie, Junxia
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Dove 2021
Konular:
Commentary
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC8217840/
https://ncbi.nlm.nih.gov/pubmed/34168481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/JIR.S301531
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