Corynoxine Protects Dopaminergic Neurons Through Inducing Autophagy and Diminishing Neuroinflammation in Rotenone-Induced Animal Models of Parkinson’s Disease

Recent studies have shown that impairment of autophagy is related to the pathogenesis of Parkinson’s disease (PD), and small molecular autophagy enhancers are suggested to be potential drug candidates against PD. Previous studies identified corynoxine (Cory), an oxindole alkaloid isolated from the C...

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Vydáno v:Front Pharmacol
Hlavní autoři: Chen, Leilei, Huang, Yujv, Yu, Xing, Lu, Jiahong, Jia, Wenting, Song, Juxian, Liu, Liangfeng, Wang, Youcui, Huang, Yingyu, Xie, Junxia, Li, Min
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2021
Témata:
Pharmacology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8078868/
https://ncbi.nlm.nih.gov/pubmed/33927622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.642900
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