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SIRT2 promotes murine melanoma progression through natural killer cell inhibition

SIRT2, an NAD(+)-dependent histone deacetylase, has been shown to play a pivotal role in various physiological processes, however, its role in cancer is currently controversial. In recent years, SIRT2 has been described as both a tumor suppressor and oncogene with divergent expression and function i...

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Detalles Bibliográficos
Publicado en:Sci Rep
Main Authors: Zhang, Manchao, Acklin, Scarlett, Gillenwater, John, Du, Wuying, Patra, Mousumi, Yu, Hao, Xu, Bo, Yu, Jianhua, Xia, Fen
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2021
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8217567/
https://ncbi.nlm.nih.gov/pubmed/34155309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-92445-z
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