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SIRT2 protects peripheral neurons from cisplatin-induced injury by enhancing nucleotide excision repair

Platinum-based chemotherapy–induced peripheral neuropathy is one of the most common causes of dose reduction and discontinuation of life-saving chemotherapy in cancer treatment; it often causes permanent impairment of quality of life in cancer patients. The mechanisms that underlie this neuropathy a...

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Bibliographische Detailangaben
Veröffentlicht in:J Clin Invest
Hauptverfasser: Zhang, Manchao, Du, Wuying, Acklin, Scarlett, Jin, Shengkai, Xia, Fen
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7260000/
https://ncbi.nlm.nih.gov/pubmed/32134743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI123159
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