Impaired stem cell differentiation and somatic cell reprogramming in DIDO3 mutants with altered RNA processing and increased R-loop levels

Embryonic stem cell (ESC) differentiation and somatic cell reprogramming are biological processes governed by antagonistic expression or repression of a largely common set of genes. Accurate regulation of gene expression is thus essential for both processes, and alterations in RNA processing are pre...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Fütterer, Agnes, Talavera-Gutiérrez, Amaia, Pons, Tirso, de Celis, Jesús, Gutiérrez, Julio, Domínguez Plaza, Verónica, Martínez-A, Carlos
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8217545/
https://ncbi.nlm.nih.gov/pubmed/34155199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-021-03906-2
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