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Efficient Immunization of BALB/c Mice against Pathogenic Brucella melitensis and B. ovis: Comparing Cell-Mediated and Protective Immune Responses Elicited by pCDNA3.1 and pVAX1 DNA Vaccines Coding for Omp31 of Brucella melitensis
BACKGROUND: Brucella spp. are intracellular pathogens, therefore cell-mediated immunity is the main response to inhibit survival and growth of the bacteria in vertebrate host. OBJECTIVE: Many eukaryotic plasmid vectors are being used in setting up DNA vaccines which may show different efficiencies i...
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| Publicado no: | Iran J Biotechnol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Institute of Genetic Engineering and Biotechnology
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8217529/ https://ncbi.nlm.nih.gov/pubmed/34179193 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.30498/IJB.2021.2618 |
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