Efficient Immunization of BALB/c Mice against Pathogenic Brucella melitensis and B. ovis: Comparing Cell-Mediated and Protective Immune Responses Elicited by pCDNA3.1 and pVAX1 DNA Vaccines Coding for Omp31 of Brucella melitensis

BACKGROUND: Brucella spp. are intracellular pathogens, therefore cell-mediated immunity is the main response to inhibit survival and growth of the bacteria in vertebrate host. OBJECTIVE: Many eukaryotic plasmid vectors are being used in setting up DNA vaccines which may show different efficiencies i...

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Vydáno v:Iran J Biotechnol
Hlavní autoři: Harzandi, Naser, Aghababa, Haniyeh, Khoramabadi, Nima, Tabaraie, Termeh
Médium: Artigo
Jazyk:Inglês
Vydáno: National Institute of Genetic Engineering and Biotechnology 2021
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8217529/
https://ncbi.nlm.nih.gov/pubmed/34179193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.30498/IJB.2021.2618
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