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Synthesis of [(211)At]4-astato-L-phenylalanine by dihydroxyboryl-astatine substitution reaction in aqueous solution

Astatine-211 ((211)At)-labeled phenylalanine is expected to be a promising agent for targeted alpha-particle therapy for the treatment of patients with glioma. The existing reactions to prepare the labeled compound usually require organic solvents and metals that are toxic and hazardous to the envir...

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Podrobná bibliografie
Vydáno v:Sci Rep
Hlavní autoři: Shirakami, Yoshifumi, Watabe, Tadashi, Obata, Honoka, Kaneda, Kazuko, Ooe, Kazuhiro, Liu, Yuwei, Teramoto, Takahiro, Toyoshima, Atsushi, Shinohara, Atsushi, Shimosegawa, Eku, Hatazawa, Jun, Fukase, Koichi
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8217504/
https://ncbi.nlm.nih.gov/pubmed/34155314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-92476-6
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