Enhancement of (211)At Uptake via the Sodium Iodide Symporter by the Addition of Ascorbic Acid in Targeted α-Therapy of Thyroid Cancer

(211)At is an α-emitter that has similar chemical properties to iodine and is used in targeted α-therapy. In the present study, we added ascorbic acid (AA) to (211)At solution to increase the radiochemical purity of astatide and evaluated its efficacy against differentiated thyroid cancer, which is...

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Bibliografische gegevens
Gepubliceerd in:J Nucl Med
Hoofdauteurs: Watabe, Tadashi, Kaneda-Nakashima, Kazuko, Liu, Yuwei, Shirakami, Yoshifumi, Ooe, Kazuhiro, Toyoshima, Atsushi, Shimosegawa, Eku, Fukuda, Mitsuhiro, Shinohara, Atsushi, Hatazawa, Jun
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Society of Nuclear Medicine 2019
Onderwerpen:
Theranostics
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6735285/
https://ncbi.nlm.nih.gov/pubmed/30796173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.118.222638
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