Theranostics Targeting Fibroblast Activation Protein in the Tumor Stroma: (64)Cu- and (225)Ac-Labeled FAPI-04 in Pancreatic Cancer Xenograft Mouse Models

Fibroblast activation protein (FAP), which promotes tumor growth and progression, is overexpressed in cancer-associated fibroblasts of many human epithelial cancers. Because of its low expression in normal organs, FAP is an excellent target for theranostics. In this study, we used radionuclides with...

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發表在:J Nucl Med
Main Authors: Watabe, Tadashi, Liu, Yuwei, Kaneda-Nakashima, Kazuko, Shirakami, Yoshifumi, Lindner, Thomas, Ooe, Kazuhiro, Toyoshima, Atsushi, Nagata, Kojiro, Shimosegawa, Eku, Haberkorn, Uwe, Kratochwil, Clemens, Shinohara, Atsushi, Giesel, Frederik, Hatazawa, Jun
格式: Artigo
語言:Inglês
出版: Society of Nuclear Medicine 2020
主題:
Theranostics
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7198371/
https://ncbi.nlm.nih.gov/pubmed/31586001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.119.233122
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