Theranostics Targeting Fibroblast Activation Protein in the Tumor Stroma: (64)Cu- and (225)Ac-Labeled FAPI-04 in Pancreatic Cancer Xenograft Mouse Models

Fibroblast activation protein (FAP), which promotes tumor growth and progression, is overexpressed in cancer-associated fibroblasts of many human epithelial cancers. Because of its low expression in normal organs, FAP is an excellent target for theranostics. In this study, we used radionuclides with...

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Detalles Bibliográficos
Publicado en:J Nucl Med
Main Authors: Watabe, Tadashi, Liu, Yuwei, Kaneda-Nakashima, Kazuko, Shirakami, Yoshifumi, Lindner, Thomas, Ooe, Kazuhiro, Toyoshima, Atsushi, Nagata, Kojiro, Shimosegawa, Eku, Haberkorn, Uwe, Kratochwil, Clemens, Shinohara, Atsushi, Giesel, Frederik, Hatazawa, Jun
Formato: Artigo
Idioma:Inglês
Publicado: Society of Nuclear Medicine 2020
Assuntos:
Theranostics
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7198371/
https://ncbi.nlm.nih.gov/pubmed/31586001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.119.233122
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