Genomic imprinting in mouse blastocysts is predominantly associated with H3K27me3

In mammalian genomes, differentially methylated regions (DMRs) and histone marks including trimethylation of histone 3 lysine 27 (H3K27me3) at imprinted genes are asymmetrically inherited to control parentally-biased gene expression. However, neither parent-of-origin-specific transcription nor impri...

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Udgivet i:Nat Commun
Main Authors: Santini, Laura, Halbritter, Florian, Titz-Teixeira, Fabian, Suzuki, Toru, Asami, Maki, Ma, Xiaoyan, Ramesmayer, Julia, Lackner, Andreas, Warr, Nick, Pauler, Florian, Hippenmeyer, Simon, Laue, Ernest, Farlik, Matthias, Bock, Christoph, Beyer, Andreas, Perry, Anthony C. F., Leeb, Martin
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8217501/
https://ncbi.nlm.nih.gov/pubmed/34155196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-23510-4
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