Modulation of lanosterol synthase drives 24,25-epoxysterol synthesis and oligodendrocyte formation.

Small molecules that promote the formation of new myelinating oligodendrocytes from oligodendrocyte progenitor cells (OPCs) are potential therapeutics for demyelinating diseases. We recently established inhibition of specific cholesterol biosynthesis enzymes and resulting accumulation of 8,9-unsatur...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Cell Chem Biol
Asıl Yazarlar: Hubler, Zita, Friedrich, Ryan M., Sax, Joel, Allimuthu, Dharmaraja, Gao, Farrah, Rivera-León, Adrianna M., Pleshinger, Matthew, Bederman, Ilya, Adams, Drew J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2021
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC8217109/
https://ncbi.nlm.nih.gov/pubmed/33636107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2021.01.025
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller