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Endosome Dysregulation in Down Syndrome: A Potential Contributor to Alzheimer Disease Pathology

Intracellular protein trafficking via the endosomes plays a key role in the maintenance of normal neuronal function. Although many diseases of the central nervous system exhibit specific pathological hallmarks, abnormalities of the endosome system are common traits for several of them, including Alz...

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Vydáno v:Ann Neurol
Hlavní autoři: Filippone, Alessia, Praticò, Domenico
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley & Sons, Inc. 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8217102/
https://ncbi.nlm.nih.gov/pubmed/33547827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.26042
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