The EMT transcription factor Snai1 maintains myocardial wall integrity by repressing intermediate filament gene expression

The transcription factor Snai1, a well-known regulator of epithelial-to-mesenchymal transition, has been implicated in early cardiac morphogenesis as well as in cardiac valve formation. However, a role for Snai1 in regulating other aspects of cardiac morphogenesis has not been reported. Using geneti...

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Udgivet i:eLife
Main Authors: Gentile, Alessandra, Bensimon-Brito, Anabela, Priya, Rashmi, Maischein, Hans-Martin, Piesker, Janett, Guenther, Stefan, Gunawan, Felix, Stainier, Didier YR
Format: Artigo
Sprog:Inglês
Udgivet: eLife Sciences Publications, Ltd 2021
Fag:
Cell Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8216718/
https://ncbi.nlm.nih.gov/pubmed/34152269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.66143
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