Intermediate filament transcription in astrocytes is repressed by proteasome inhibition

Increased expression of the astrocytic intermediate filament protein glial fibrillary acidic protein (GFAP) is a characteristic of astrogliosis. This process occurs in the brain during aging and neurodegeneration and coincides with impairment of the ubiquitin proteasome system. Inhibition of the pro...

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Detalhes bibliográficos
Main Authors: Middeldorp, Jinte, Kamphuis, Willem, Sluijs, Jacqueline A., Achoui, Dalila, Leenaars, Cathalijn H. C., Feenstra, Matthijs G. P., van Tijn, Paula, Fischer, David F., Berkers, Celia, Ovaa, Huib, Quinlan, Roy A., Hol, Elly M.
Formato: Artigo
Idioma:Inglês
Publicado em: The Federation of American Societies for Experimental Biology 2009
Assuntos:
Research Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3221645/
https://ncbi.nlm.nih.gov/pubmed/19332645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.08-127696
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