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Reactive astrocytes as treatment targets in Alzheimer's disease—Systematic review of studies using the APPswePS1dE9 mouse model

Astrocytes regulate synaptic communication and are essential for proper brain functioning. In Alzheimer's disease (AD) astrocytes become reactive, which is characterized by an increased expression of intermediate filament proteins and cellular hypertrophy. Reactive astrocytes are found in close...

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Dades bibliogràfiques
Publicat a:Glia
Autors principals: Smit, Tamar, Deshayes, Natasja A. C., Borchelt, David R., Kamphuis, Willem, Middeldorp, Jinte, Hol, Elly M.
Format: Artigo
Idioma:Inglês
Publicat: John Wiley & Sons, Inc. 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8247905/
https://ncbi.nlm.nih.gov/pubmed/33634529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/glia.23981
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