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Optimizing mitochondrial maintenance in extended neuronal projections

Neurons rely on localized mitochondria to fulfill spatially heterogeneous metabolic demands. Mitochondrial aging occurs on timescales shorter than the neuronal lifespan, necessitating transport of fresh material from the soma. Maintaining an optimal distribution of healthy mitochondria requires an i...

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Bibliografski detalji
Izdano u:PLoS Comput Biol
Glavni autori: Agrawal, Anamika, Koslover, Elena F.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2021
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8216566/
https://ncbi.nlm.nih.gov/pubmed/34106921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1009073
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