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The H3K36me2 methyltransferase NSD1 modulates H3K27ac at active enhancers to safeguard gene expression
Epigenetics, especially histone marks, functions beyond the DNA sequences to regulate gene expression. Depletion of NSD1, which catalyzes H3K36me2, leads to both up- and down-regulation of gene expression, indicating NSD1 is associated with both active and repressed gene expression. It's known...
שמור ב:
| הוצא לאור ב: | Nucleic Acids Res |
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| Main Authors: | , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Oxford University Press
2021
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8216457/ https://ncbi.nlm.nih.gov/pubmed/34107030 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkab473 |
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