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Cooperative DNA looping by PRC2 complexes

Polycomb repressive complex 2 (PRC2) is an essential protein complex that silences gene expression via post-translational modifications of chromatin. This paper combined homology modeling, atomistic and coarse-grained molecular dynamics simulations, and single-molecule force spectroscopy experiments...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Main Authors: Lin, Xingcheng, Leicher, Rachel, Liu, Shixin, Zhang, Bin
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8216278/
https://ncbi.nlm.nih.gov/pubmed/34057467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkab441
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