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The nuclear periphery is a scaffold for tissue-specific enhancers

Nuclear architecture influences gene regulation and cell identity by controlling the three-dimensional organization of genes and their distal regulatory sequences, which may be far apart in linear space. The genome is functionally and spatially segregated in the eukaryotic nucleus with transcription...

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Dettagli Bibliografici
Pubblicato in:Nucleic Acids Res
Autori principali: Smith, Cheryl L, Poleshko, Andrey, Epstein, Jonathan A
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8216274/
https://ncbi.nlm.nih.gov/pubmed/34023908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkab392
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